CELLBANKER’s Scientific Annual Report (2021)

ZENOAQ 會定期發表關於細胞冷凍保存的研究文章。以下是2021年出版的摘要。

・2021年ZENOAQ的研究文章發佈共 178 篇，創歷史新高。

・The number of the cited scientific articles was 125 (contain preprints).

・2021年的研究文章曾多次在許多著名的科學期刊上發表。

(包括 Nature, Cell Stem Cell, Nature Protocols, Nature Communications, Proc Natl Acad Sci USA, The EMBO Journal, Cell Reports, Science Advances, Scientific Reports, STAR Protocols 等等)

Preserved Samples /CELLBANKER type	Articles
cGMP manufactured MSK-DA01 cells /STEM-CELLBANKER	Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01. Piao J, et al., Center for Stem Cell Biology, Memorial Sloan Kettering Cancer Center, New York, *Cell Stem Cell, 2021, 28(2):217-229.e7. Parkinson’s Disease Preclinical Study*
Naïve human PSC derived trophectoderm, Naïve PSC-derived cytotrophoblast /STEM-CELLBANKER	Capturing human trophoblast development with naive pluripotent stem cells in vitro. Io S, et al., Department of Life Science Frontiers, CiRA, Kyoto University, *Cell Stem Cell, 2021, 28(6):1023-1039.e13. Organoid Study*
Tumor-derived spheroids from uterine endometrial and ovarian malignant tissues /STEM-CELLBANKER DMSO Free	Establishment of in vitro 3D spheroid cell cultivation from human gynecologic cancer tissues. Ueda H, et al., Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, *STAR Protocols, 2021, 2(1):100354. Spheroids*
Tumor samples for preimplantation /STEM-CELLBANKER DMSO Free	Characterization of the large-scale Japanese patient-derived xenograft (J-PDX) library. Yagishita S, et al., Division of Molecular Pharmacology, National Cancer Center Research Institute, *Cancer Science, 2021, 112(6):2454-2466. PDX Model Study*
Human PBMC /含血清細胞凍存液 CELLBANKER 1	mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants. Wang Z, et al., Laboratory of Molecular Immunology, The Rockefeller University, New York, *Nature, 2021, 592: 616–622. COVID-19 Study*
iPSC derived foregut cells /含血清細胞凍存液 CELLBANKER 1	High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell–Derived Organoids. Shinozawa T, et al., Developmental Biology and Center for Stem Cell and Organoid Medicine (CuSTOM), Cincinnati Children’s Hospital Medical Center, *Gastroenterology, 2021, 160(3): 831-846.e10. Organoid Study*
CAR-T cells /無血清細胞凍存液 CELLBANKER 2	Peripheral leukemia burden at time of apheresis negatively affects the clinical efficacy of CART19 in refractory or relapsed B-ALL. Deng B, et al., Cytology Laboratory, Beijing Boren Hospital, Beijing, *Molecular Therapy – Methods & Clinical Development, 2021, 23: 633-643. CAR-T Cell Study*
Liver tissues /無血清細胞凍存液 CELLBANKER 2	Regional Differences in Human Biliary Tissues and Corresponding in Vitro Derived Organoids. Rimland CA, et al., Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, *Hepatology, 2021, 73(1):247-267. Organoid Study*